If the motherboard adheres to ATX spec, then it should fit. This is likely. The issue is more likely to be with the case than the board as a lot of cases only give the recommended 3 inch space over the socket, and some coolers are taller than this.
A thermalright TRUE with a fan strapped to either side was a comfortable fit on my P5Q premium, and that looked massive. If really unsure though, I'm sure ocuk would tell you if you asked them via webnote.