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Only do it if you are having problems - some games like BF4 if you need to do it you will notice them stuttering badly at times, etc.
Largely it doesn't put significant extra stress on a desktop system but you might find it produces a little extra heat on laptop i7s which might not be ideal - I've got the tweak done on both of the i7 systems in my sig without any issues.
what op you using, i used the reg hack method on win 7 but its not needed on win 10
what op you using, i used the reg hack method on win 7 but its not needed on win 10