Vista slowing down - tips?

[laissez-faire]

Have had Vista installed for about 6 months now and it is starting to slow down. Short of doing a complete format what tips are there to speed it back up to that 'out-of-the-box' type speed? So far I have defragmented the hard disc.

Cheers,

Sam

 

[Lydzor]

Running Ad-aware and CCleaner could help.