To be honest the Bamboo range are great if you want a travel tablet. IE one that will slip inside your laptop bag and just give you a better input device for quick touch ups on location or whatever, but really the only Wacoms worth owning for desktop use are the Intuos range. The pens are miles better for a start, and are comfortable to use for long periods. They're heavier and more ergonomic with rubber grips, and the tablets themselves are just of higher quality and more importantly go bigger (too small a tablet is just a pain if you're matching it up to even a reasonably common desk screen like a 24").
If I were you I'd save a couple more pennies and maybe look at the second hand Intuos 3's on eBay, get the biggest you can afford. They last forever so the fact it's second hand really isn't an issue unless it's been constantly dropped or something.
Otherwise if you're feeling rich the Intuos4 are the cream of the crop (for separate tablets) and well worth every penny in my opinion.
The above advice does depend on how often you plan to use it though. I don't actually have a mouse plugged into my work computer so comfort in use is paramount to me, and I could never use a Bamboo day in day out.