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More information is needed. What is your budget and screen resolution?
What CPU you using by the way? Just checking to make sure you won't get CPU bottleneck...I've seen people got a 5870 paired up with a stock speed E6750 >_<
+1 sounds good5850Oc it, and oc the 750. Sorted
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I'd go for the 5850 as well, best value for money. 5770 cf would give good performance, but then you have to deal with the odd driver issue/lack of game support, and for the same price (less actually) you could have a great single card which leaves you the option of cf at a later date when 5850s are even cheaper.