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There was some reason for this that I can't quite remember ...
Many high end cases actually invert the whole motherboard ... 900D, PowerMac G5/Mac Pro, some larger Silverstone and Lian Li cases ...
It's a set of 3x2GB and 3x1GB
RAM mis-matching ... how terrible
Actual answer:
"We used to have ISA slots. The cards were right-side-up. When PCI was being developed, designers wanted to give builders a choice of using up to six PCI cards or six ISA cards from a single 8-slot AT case. To geth PCI and ISA to serve the same slot hole in the case, the PCI slots were placed between the ISA slots. Then, to get them to align with the hole, they were made upside-down.
With this design you could have an ISA card one slot above the PCI card and still have enough room between them to prevent shorts, and motherboard designers didn't have to take away one slot to add the other.
AGP followed PCI design, the PCIe followed AGP design."
I think they look nicer on water this way up.
My next job, do something about the crap red power leads.
Inverted atx cases are great for watercooling