yes it will definitely handle it, you might just have to have the fans on to a point where they're audible.
I have a PA120.3 with my 8800GTX, NB, SB, Mosfets and RAM in one loop (got the CPU on its own in another 120.3) and both loops are passive, no fans. So I can't see why with moderate fans you couldn't have the load you suggested.
Even gaming you are unlikely to manage 100% load on it all anyway.
If you're concerned try and get your fan arrangement to push/pull (ie fans on both sides) that really will seal the fact it will cope.