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The prefectchers inside the chips are optimised to perform server and rendering applications, whereas inside the regular desktop chips they are optimised for day to day applications such as gaming and web browsing. I imagine that the difference you would see in day to day performance would be tiny, and loads of people use the xeons (and for that matter, opterons) as desktop computers. Some people have mentioned that they are made on a higher quality silicon wafer, which means that they should last longer and clock better, although i have no idea if this is true. However, Xeons in general seem to require a lower vcore to reach the same clocks as the equivalent desktop chips, and are usually more expensive.
