Yes, migrated my ZFS NAS from FreeNAS to CentOS a couple of years ago, and recently migrated from CentOS to Ubuntu 20.04 LTS.
It's been solid, I've got some decent HGST drives and I'm using mirrored VDEV's with ECC ram.
The one thing I really don't like, It's slow, really slow.
It's sort of OK ish for smaller file reads, the 32G ECC is just enough to maintain decent ARC cache but reading or writing large files, VM images, media that sort of thing is painful. I don't have room in the box for a faster disk for an L2ARC cache to help deal with that