I've had quite a few problems with SSDs (two failed Vertex LE drivers, bluescreens on my Vertex 3) but the difference in performance is huge, so I won't be changing back to HDDs. It depends what you expect from a computer. Personally I think a few issues are worth the performance gain and I make sure I regularly image my primary drive.
Would I use an SSD in a critical system? Absolutely not. Would I use it for a gaming / personal computer? Definitely. But I'll be sticking to 120GB SSDs for my OS drive until they offer a 1.5-2TB performance SSD for a reasonable price, as my Steam folder is over 1TB - that will probably be another 2-3yrs, which should be enough time for reliability to mature. Until then I'll keep all non-OS data on my HDDs.