Well, first impression are great.  Your given a budget of £500,000 and a wage budget of £100,000.  You can auto-select your squad, where you put in your fav team, country and it auto selects you a squad.  You can also pick each member of your squad individually which is what I did.  There is an acquisition fee for each player which uses up your £500,000.  
Once you've got your squad together you choose a Football Association to be in.  There are ones for hardcore players who play 24/7, early evening, night-time, morning, etc.  I joined the All Evening FA, so I am most likely to get games against opponents in my league from 6-12pm.  The league starts on Friday so at the moment I'm just playing friendlys and getting my reputation up.  Pittodrie Ultras FC (my team 

)  have played 2 friendlys - drew first 0-0, won second game 2-1.  So yeah, it's great so far