You dont need to mod anything, here's corsair talking about the antec 300 and upside down mounting of the PSU. It may be different for other companies but I doubt it.
"If the PSU sits flush against the bottom of your case then I would install it upside down. If you have even a few millimeters underneath the PSU, then you should be able to install it right side up."
So its fine either way.
Also to the above poster PSU's suck air in and expel it out the back.