Oh man I've been so excited ever since I saw the trailer with the 'nids!
I must say I'm slightly ambivalent, but more because it wasn't quite what I was expecting. Kudos to relic though, I love that they're trying to keep things fresh and moving forwards, not making C&C 45. It's what I liked about DoW (that and the 40k universe is just awesome) and CoH.
I was expecting more traditional style RTS shizz. But the Diablo/CoH cross is working pretty well for me! AS you've all been saying though, it does make me wonder about multiplayer.
Roll on Q1 '09!