You asked:
1. Am I right in thinging these TFC fittings will screw into the koolance stuff if I chose to go down that route?
2. Also don't know if you answered my question and I just ignored it! But, do I need seperate resevoirs/radiators for say CPU/chipset and GPU?
3. I only have a 600w zalaman PSU, will I need to uprate it?
1. Yes generally speaking 80% of the pc watercooling components on the market today use what is referred to as G1/4" thread (could someone in the 'know' tell me what this refers to??!). The TFC compression fittings are FANTASTIC because they secure tightly into these threads simply by hand instead of barbs. I am unsure about Koolance having never used any of their blocks but XSPC, EK, Alphacool, Petra etc etc all use this type of thread on their stuff.
However, the undisputed 'king of cool' radiator line (namely the Thermochill PA120 series) uses a 3/8 thread. This means that if for example, you were to try and screw a TFC compression fitting into the thread on said radiator it wouldn't work! Although, you can get thread adapters of course! Also, the Thermochills use slightly different fan spacing which makes them a pain to mount (unless you dont mind modding) anyhow I digress...
You would need to check the specs on the Koolance blocks you were interested in but in all likelyhood they, like the rest of the manufacturers use the G1/4" thread ie. Compatible with most fittings/barbs.
2. You should only need one resevoir in your loop. However, as far as radiators go it all depends on what you are cooling. Let's say you were going to cool your GPU and CPU - a triple radiator mounted in the top of your case would be fine. Although I would highly recommend grabbing a high-performance rad such as the previously mentioned TFC Exchanger. If you bought a second GTX295 and wanted to go Quad SLI then I would say you would need to look at getting a second single rad installed in the exhaust 120mm fan slot at the back of your cosmos. You could either then, incorporate this 2nd single radiator into your single loop or split your loop into two (although then you would need another resevoir and pump). Having said this however, a single probably wouldn't cut it with another 295 and then you would have to decide what components got the benefit of the triple over the single...*
So to summarise, no you do not need seperates UNLESS you were planning on adding another HOT component to your loop. The Laing DDC Ultra pump is VERY powerful and should cope fine with a single loop comprising of multiple blocks.
3. If I was you then yes. I do not know how much power drain a pump sups but I seem to remember 30w from an old issue of CustomPC?! Don't quote me on it though! Personally, my concern would be the GTX295. It's essentially 2xGTX260s right?! I'd say 600w is the bare minimum although there is a lot of misinformation going round the net atm. No-one needs 1000W and above unless they are running NASA. For you, I would recommend a 850W or greater just to be on the safe side. The Be Quiet! range of PSUs are very good.
Sorry for the long post but I hope the information I have provided has been of some use to you!
Tom
* As a side note, you should look at the Silverstone TJ07 case. It has room at the bottom for a Thermochill PA120.3 and a normal triple radiator can be roof-mounted at the top of the case with a little modding.