+1
Always nice to see someone glancing at you constantly, then start flirting outrageously with you...
Just need to make sure you can then think of something to say after the "where are you from?" questions are used up...

I struggle with that when drunk, my ability to actually thing of anything useful to say goes out of the window really, unless the girl shares some proper common interests with me (which is hard to find out within a very short convo).
Luckily I tend to stick to just being on the dance floor or by the bar on a typical night out, so there isn't much time for a convo anyway especially with all the loud music that UK clubs have.
One night was funny, the girl wanted to have a proper convo, but ended up losing her voice lol, so it was conducted by her typing out what she wants to say on my phone and me conversing while laughing uncontrollably at her.
Anyway, back on topic. Conversation at the time of meeting is not as important in a nightclub, unless you are in a REALLY trendy place - most, as mentioned before, simply have the music on too loud.
Being cheeky/cocky, decent looking, and wearing something that stands out from the crowd works for me (but damn is it hard to stand out on a night that is already fancy dress themed!). Having a hat is just awesome as well, girls LOVE to try it on, get some pics taken.
Just beware of jealous blokes who will throw the hat half-way across the club and of cheeky girls who will steal the hat from you and never give it back.
Another thing that works well in a club scene, is quicker escalation (via dancing which allows for close contact at times) which can allow you to by-pass the conversation part until some other day (and can even be done via text/msn/facebook). Just remember to get a phone number or the girl's name to find them on facebook
(I have at times got caught up in the dancing / kissing that I actually failed to ask for the girl's name, let alone a phone number lol) - though generally if the girl is interested in you she'll prod you to take her number, or for her to find you on facebook, or whatever.
And why am I sounding like Will Smith from Hitch :/