The only "problem" I've had is that it beachballs a fair bit... plus feature wise (just things like proper extensions and the fact that while you're closing tabs they dont resize 

) chrome is just bucket loads better...
So, heres what I've done, and it works really, really well...
• On my work computer (iMac) which is always on in the office for the purpose of offsite backing up at 3am and the like I have installed Chrome, Xmarks for Chrome, and Xmarks for Safari.
• Then on every other mac, I just install Chrome, and switch on the (very solid, and built in) Google Sync to sync my bookmarks and settings etc (but I don't sync extensions since I dont want to run Xmarks on every other computer apart from my work one).
• Now when I make an amendment to say the Chrome bookmarks on my MBA, it syncs lightning fast to my work Chrome, which in turn syncs to Safari via Xmarks, which in turn pushes any changes out to all my other Safari's, including on my iPhone 
All in all, this works ace, and doesn't require any additional software and extensions except for 2 installs (Chrome and Safari) of Xmarks on 1 computer 
Bargain 
