By 'setting up' you imply that this computer will be brought out when needed then put away again?
If so, depending on how much time and effort you're willing to put in, i suggest mounting the computer into a rack/flight case/cabinet on wheels and building a simple connection panel with clear labels - video, sound, and so on.
Back in my radio days, we used to receive a pre-racked radio transmitter (hired) with a handful of cables coming out the back - apply power and audio and hey presto we had a full FM radio transmitter set up and running, it saved a lot of time.