I personally wouldn't in any way move to a £300 mobo just to get better spacing.
Honestly, I'd go with a new case, because it will only help in the future. It will allow more options in terms of 3rd party cooling and future sli/xfire setups as you have more space.
I ended up going with a Haf, mostly because my older THermaltake Armour +(its HUGGGGEE) had a broken door panel and Thermaltake just ignore EU e-mails, couldn't sort out the right panel and without it well, cats who push my door open + computer on +nosey = bad
ANyway the Haf has a decent space between PSU and bottom of mobo, inteligently a little space above the mobo so doing things like attaching the cpu 8pin is actually manageable, and good cooling with all the fans set to run very quietly.
ANyway if that lets you run the current setup with gpu in the bottom slot thats great, if its a 4x slot I'm not sure thats the best way to go, but probably 16/8/8 on a x58 mobo.
If you had to change mobo though, I'd just ditch the mobo, and the cpu, and get a much cheaper 2500k setup, better mobos(when they work) and far better spacing. Its those daft heatsinks on the stupidly placed northbridge making so many of those x58 boards lose a few slots at the top.
Something along the lines of
http://www.overclockers.co.uk/showproduct.php?prodid=MB-166-MS&groupid=701&catid=5&subcat=1906 mSi p67 mobo, + 2500K is basically the same price as a £300 x58 mobo.
Obviously it depends, do you need 12gb mem for anything(as you'd be down to 4 mem slots).
hell you might be able to sell your cpu/mobo, buy a Sandybridge cpu/mobo break even. In most things it would be faster you can get any of a range of vastly cheaper just as good mobo's. You'd only be losing memory bandwidth you really don't need.