The MS Wireless receiver is a known problem, however, I sent a revision 3 unit out to HQ and they've managed to replicate and find a fix for the pointer drift. We should have a system-wide update ready for this shortly.
The two keyboard/mouse report during BOOT is something to do with UEFI - it's just a report error and unrelated to the issue above (I will get that back to HQ anyway).
I will check up on the fan report and the Intel LAN drivers.
That leaves the AGESA optimization for the upcoming architectures which means the older processors are going to need some manual tuning - we can't do much about that as it currrently stands unless AMD opens up more of the microcode for manipulation.
The ROG forum registration info requirements should be the same as any other forum AFAIK.
Beta BIOS 009 fixes a few memory timing issues so might be worth checking that out - I will link the BIOSes in the ASUS official AMD support thread on this forum.