We stay in Costa Adeje when we go, a bit quieter (ok a lot quieter) than las americas, but within reasonable traveling distance should you want a 'big night out'
Weather is fantastic - so if you enjoy the sunshine you are in luck.
This year we went to loro parque, which is in the north of the island. Brilliant animal park, up there with seaworld in florida in my eyes.
We also went to Siam Park which is a fairly new water park in the south of the island. It really is world class and perhaps my favorite water park yet.