Fatties gonna fat....

Don't fret, he's here now!

Fat people can't help their genetics, you know. It's the fat gene that makes them fat.
http://en.wikipedia.org/wiki/Genetics_of_obesity

Try reading before attempting to sound intelligent.

"The thrifty gene hypothesis postulates that due to dietary scarcity during human evolution people are prone to obesity. Their ability to take advantage of rare periods of abundance by storing energy as fat would be advantageous during times of varying food availability, and individuals with greater adipose reserves would more likely survive famine. This tendency to store fat, however, would be maladaptive in societies with stable food supplies.

This is the presumed reason that Pima Indians, who evolved in a desert ecosystem, developed some of the highest rates of obesity when exposed to a Western lifestyle."

There are literally hundreds of studies showing links, along with twin studies, FMO, leptin deficiencies & a whole series of associated genes. This is ignoring the myriad of environmental & psychological issues which sit alongside these.

I guess ignorance is easier.
 
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Even if true, that doesn't excuse becoming morbidly obese tho, does it. People who become too fat to work *know* they are eating too much.
 
Please think about it.

Both are huge factors, a portion of the population has a genetic weakness to the change in the availability of food, the other group doesn't.

Both factors (along with many others) matter immensely & both contribute towards obesity.

But it apparently accounts for about 5%... so really it is a question of perspective

Lifestyle and diet are the biggest factors by far
 
Even if true, that doesn't excuse becoming morbidly obese tho, does it. People who become too fat to work *know* they are eating too much.
If true?, it is true.

It means that person A gains fat at a significantly faster rate than person B, assuming an equal diet one ends up obese & the other slender. A person may be eating too much for their bodyweight indeed, but a may still be genuinely hungry (if the problem is related to appetite).

A hungry person will eventually eat. It makes no rational or logical sense to judge people based on weight when we may be the beneficiaries of fortunate genetics.

But it apparently accounts for about 5%... so really it is a question of perspective

Lifestyle and diet are the biggest factors by far
Just no.

That's the population for the Mrap2 gene, if you read below for the FTO gene (which is far more common).

"According to HapMap, it has population frequencies of 45% in the West/Central Europeans, 52% in Yorubans (West African natives) and 14% in Chinese/Japanese. Furthermore morbid obesity is associated with a combination of FTO and INSIG2 single nucleotide polymorphisms."

Which fits the findings as Japan has one of the lowest obesity rates in the developed world, as does Korea.

Again, it's not a singular factor - but it's a strong indicator & for many determines if a person has the propensity to become obese (given other factors).

Of course people should still try to diet & exercise - along with resolving any underline issues which may cause them to be unable to control eating, depression, lack of motivation where possible. But, I don't think the rest of society who are likely just the beneficiaries of good genes/environment & upbringing should insult & look down on those who are obese/over-weight.

Finally, those who are obese should stop beating themselves up over it with self loathing - take some comfort in the knowledge there are reasons why it's harder for many of them & perhaps with this be more able to put meaningful steps in place to address the issue (instead of continuing a cycle of self-loathing & depression).
 
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If true?, it is true.

It means that person A gains fat at a significantly faster rate than person B, assuming an equal diet one ends up obese & the other slender.

So person A has to exercise more and eat less, then. In other words, work harder.

Is genetics a valid excuse to throw your hands in the air and give up? To let yourself go?

Plenty of people of average intelligence become engineers or whatever. They just work harder to get there. Should they give up and say "Genetics didn't make me a genius, I'll just stack shelves then."
 
So person A has to exercise more and eat less, then. In other words, work harder.

Is genetics a valid excuse to throw your hands in the air and give up? To let yourself go?

Plenty of people of average intelligence become engineers or whatever. They just work harder to get there. Should they give up and say "Genetics didn't make me a genius, I'll just stack shelves then."
Yes, so if half the population have to exercise more & eat less than the other half doesn't that in part explain why we have such a difference in bodyweight across the population?.

Who is suggesting they give up?, nobody - stop talking rubbish.

I'm saying we need to stop the overly simplified idiotic judgemental attitudes towards people who objectively have to work significantly harder than many of us for the same thing. I'm in no way suggesting that people with a stacked deck against them should give up, quite the opposite - I'm saying that the rest should stop making it harder for them by creating a cycle of self-loathing & depression.

I'm all for real assistance, good dietary advice, support, good exercise tips (some great guys in the weightlifting threads for exactly that on this forum), psychological support for those with deeper issues & to continue to research & study other factors which may impact on weight gain, appetite & weight loss.

Just calling people who are over-weight "Fat & lazy" - ironically is stupid & lazy (double irony is intentional).
 
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A hungry person will eventually eat. It makes no rational or logical sense to judge people based on weight when we may be the beneficiaries of fortunate genetics.

Just no.
Hunger can and is dramatically affected by what you consume.

Have some theories(and references!):
http://www.csun.edu/~vcpsy00h/students/hunger.htm

(Ignoring heat production theory as it's not all year round)

Glucose theory states that we feel hungry when our blood glucose level is low. Bash (as cited in Franken, 1994) conducted an experiment transfusing blood from a satiated dog to a starved dog. The transfusion resulted in termination of stomach contraction in the starved dog, and supported the glucose theory.

Insulin theory states that we feel hungry when our insulin level increases suddenly in our bodies (Heller, & Heller, 1991). However, this theory seems to indicate that we have to eat to increase our insulin level in order to feel hungry.

Fatty acid theory states that our bodies have receptors that detect an increase in the level of fatty acid. Activation of the receptor for fatty acid triggers hunger (Dole, 1956, Klein et al., 1960 cited in Franken, 1994).

Basically, (and many people believe this) the 'wrong' food will have big impacts on you glucose/ insulin and/ or fatty acid levels. Making you more hungry.

Read the rest of the link for all the other reasons why we can (and should) manage our hunger better than we do.
 
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Please think about it.

Both are huge factors, a portion of the population has a genetic weakness to the change in the availability of food, the other group doesn't.

Both factors (along with many others) matter immensely & both contribute towards obesity.

I will full allow the fact that may be the case, but I just wish people could get the right information with regards to this, as it is becoming the problem.
How much this is a factor, and it's very much like the metabolism myth, it get's thrown about like an excuse ball, you can judge me for sticking pies in my mouth, I have a high metabolism, you can't judge me, I have genetic problems.

Your wiki article says that it is possible that fat parents have a higher chance of creating fat children, so it might well be that the problem isn't the genes, it's the fat people making their genes adapt. Stop the problem before it starts.
 
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Yes, so if half the population have to exercise more & eat less than the other half doesn't that in part explain why we have such a difference in bodyweight across the population?.

You are ignoring all the people for whom being overweight is a lifestyle choice. Yes, choice.

People who "love" their food more than their health, and decide to live in a way which makes them fat.

People who then might claim disability benefits, and cost the NHS millions when they inevitably get some preventable health problem.
 
I will full allow the fact that may be the case, but I just wish people could get the right information with regards to this, as it is becoming the problem.
How much this is a factor, and it's very much like the metabolism myth, it get's thrown about like an excuse ball, you can judge me for sticking pies in my mouth, I have a high metabolism, you can't judge me, I have genetic problems.
If I link the studies with the hard data will you actually read them?. There is plenty of data if you have google & five minutes of time.

You are ignoring all the people for whom being overweight is a lifestyle choice. Yes, choice.

People who "love" their food more than their health, and decide to live in a way which makes them fat.

People who then might claim disability benefits, and cost the NHS millions when they inevitably get some preventable health problem.
How many of those are there?, or are you reading the Sun & assuming a notable portion of the population are like that?.
 
If I link the studies with the hard data will you actually read them?. There is plenty of data if you have google & five minutes of time.

I would but I'd like a spoon fed number. If #1's genes are making him gain a few grams more than #2 it seem negligable.
Surely a certainty in the data should be able to say these people are 50/60% worse off.
 
Surely a certainty in the data should be able to say these people are 50/60% worse off.
They're only worse off if they eat bad food/ get into bad eating habits and become unable to manage their hunger levels. But seeing as it is perfectly possibly to eat better and manage your hunger levels such that you only consume the number of calories required then surely it's a moot point about genetics?(see my previous post)

I.e. if the problem is appetite, and you have 'bad genetics' then the onus is still on you to manage your hunger levels correctly and eat better/ healthier foods in order to avoid tricking your brain into thinking that it's still hungry.

At best there are still more factors in play than is being suggested.
 
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How many of those are there?, or are you reading the Sun & assuming a notable portion of the population are like that?.

A notable portion of the population are like that, in the same way there is a notable portion of the population who smoke (and continue to take up smoking) despite knowing the health risks. When they are just "risks" and you haven't actually had a heart attack yet it makes it much easier to think it will never happen to you and keep putting away the curries and pints. I'm not saying this applies to everyone, but you seem to be implying that the majority of fat people are just unfortunate with their genes and would otherwise be fit and healthy.
 
How many of those are there?, or are you reading the Sun & assuming a notable portion of the population are like that?.

A notable portion of the population are like that, in the same way there is a notable portion of the population who smoke (and continue to take up smoking) despite knowing the health risks. When they are just "risks" and you haven't actually had a heart attack yet it makes it much easier to think it will never happen to you and keep putting away the curries and pints. I'm not saying this applies to everyone, but you seem to be implying that the majority of fat people are just unfortunate with their genes and would otherwise be fit and healthy.

Exactly. It's most likely the vast majority. As evidenced by the people who decide one day to lose weight and then do it. Those people prove that they aren't destined to be fat, it was a choice to get fat and another choice to lose the weight (a better choice).

We all know obese people who binge drink, for example. If they cut back on the drink, they would find the weight easier to control. But they "love their drink". Is that not their choice, rather than their genes?
 
Exactly. It's most likely the vast majority. As evidenced by the people who decide one day to lose weight and then do it. Those people prove that they aren't destined to be fat, it was a choice to get fat and another choice to lose the weight (a better choice).

We all know obese people who binge drink, for example. If they cut back on the drink, they would find the weight easier to control. But they "love their drink". Is that not their choice, rather than their genes?

Smokers and drinkers aren't victimised because of their vices, hell there are whole sections of the NHS purely for the after care of people who get cancer because of smoking. Fat people are though. How many callouts a night do you think NHS gets and how many tarted up women who binge drink hurt because they drunk so much they are paralytic and faceplanted into the pavement.

I don't walk round town sneering, pointing, looking and laughing at someone with a ciggy in their mouth.

I don't see threads on here called "smokers gonna smoke......." and 18 pages of people calling smokers weak for giving in to an addiction, or that they should just give up because it's super easy to give up, you just stop smoking!

Smokers know they are poisoning their bodies before they've even tried or got addicted to nicotine, so why don't they get as much if not more hate?
 
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I don't know if smoking is anywhere near as socially acceptable as it used to be.

Drinking(alone, for example) either, for that matter.
 
I would but I'd like a spoon fed number. If #1's genes are making him gain a few grams more than #2 it seem negligable.
Surely a certainty in the data should be able to say these people are 50/60% worse off.

Genetics is a bit more complicated than that. You can have the exact same genes (no SNPs) with the exact same promoter/enhancer regions in two different individuals that give different relative expressions.
This could be due to differing levels of transcription factors, polymerases, or tRNAS. Stochastic noise, perhaps even due to epigenetics, upstream elements or heterochromatin structure.

Basically it's complicated so you probably won't ever get a solid statistic for how much worse off someone may be than another at gaining weight.

Regardless I don't care how much worse off someone may be than another for putting on weight. It is up to them as an individual to find a diet and exercise regime specific to themselves to avoid health issues caused by obesity.
 
Yet intentionally giving yourself cancer is more accepted than weighing more than the guy next to you.
Not saying that it's more accepted. But it has never been 'cool' to be obviously overweight and that's the reality of it.

In the past(thanks to clever marketing) it has been 'cool' to be both an alcoholic and give yourself lung cancer (yes I am oversimplifying).

I'm not saying it's fair. Just giving you the facts.
 
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