Sorry to Hijack the threat but due to a misshape with a certain company i was sent an extra 980ti by mistake and currently got them SLI .
I am looking to upgrade my self and was looking at the X99 route
Lucky you - I wish OCUK had done the same when I just purchased my MSI 980 Ti Lightning - lol
Anyways, if you're going SLI and upgrading from that 2500K, then X99 would be the way to go to recognise the full performance from 980 Ti SLI at the moment. (you would see a big increase in performance)
As for which to go for rather depends on what you intend to use the rig for! - gaming or benching?
Me being a gamer, personally I would go for MSI X99A Gaming 7 USB 3.1 Motherboard @ around £200, but that's purely because I like all the usb connectors on the back and like what MSI have done recently on their boards. (I currently have the Z170A MSI Gaming 7 and find it excellent for my single card in games)
I'm sure others would recommend Gigabyte or Asus boards instead (personal preference really) - as for CPU if you can stretch to a 5930K @ about £450 then you get 6 cores and 40 PCI lanes to cover you for future needs as the 5820K only offer 28 PCI lanes.
Your 850W PSU should be good for this setup (just) and you will need 16GB ram - personally I would go for :
16GB (4x4GB) Corsair DDR4 Vengeance LPX Black PC3-24000 (3000), CAS 15-15-15-36 @ about £120 - fast but low timings and I've never had issues with Corsair memory.
You can use your current SSD but I would prefer the Samsung 256GB 850 PRO to finish off @ at about £105
For a new case, I would choose the Corsair Graphite Series 780T
Hope this helps