personally i wouldnt touch an MSI part even given to me freely after the way they have behaved recently.
But AMD seems to be the flavour recently namely the 570 boards with a new 5000 series cpu out shortly, id base a build on that and bung at least 16GB in it - no less
As regards a GPU your spoilt for choice shortly but sadly the nvidia 3000 series cards and launch have been a let down for everyone and itll be anohter month or so till you can get a 3080 - maybe.
Hard drive wise stretch for a single M.2 drive of at least 1TB the samsung EVO 970 are nice and are around £100 second hand on ebay
Id look at waiting until AMD release their GPU's first and then make an informed choice based on whats on offer. But youll get a pretty nice build for £1500
Assuming youve got an old dog of a monitor running at 1080 youll eventually need a new one, but it will do you for now.
PSU wise id go for a 1000w one and a branded one so you have headroom and itll last you years if you clean it regularly
The alternative to buying new is the way id go id go with and for me the second hand market via ebay is king and there are some good deals on high end 1151 - z390 boards and processors on ebay constantly now that will do the job perfectly well and youll save a lot of money you can then buy better parts with
If you live close id build you one for free if you supplied the parts we could sit and do it together and i could teach you how its done as ive built dozens now over two decades, there is nothing to it and there are numerous guides on youtube -
Go second hand bits and build your own bud, you wont regret it and if your in the midlands shout me