This is where the type of vehicle makes a huge difference.
100 is easy these days and doesn't require much more concentration, it's when speeds get significantly higher that your concentration increases fatigue. As long as you know your stopping rate at the speeds you're going then you can mitigate it slightly, but the risk ratio is still heavily weighted towards dangerous.
By travelling 40% faster, you're still reducing the time you have to safely react by ~40%. A quick Google suggests the average reaction time is 250ms (1/4s).
At 70mph that's ~8m covered + braking distance of 75m
At 100mph that's ~11.5m covered + braking distance of 152m
(figures above from here:
https://www.random-science-tools.com/physics/stopping-distance.htm)
To make it interesting, I found
this page which gives the results for a Porsche Cayman GT4, which has probably got better stopping power than 99% of cars on the road, which gives braking distances of ~40m @ 70mph and 73m @ 100mph.
I can't be bothered to do the exact calculations on what speed you would still be travelling at the 48m point (where you would have stopped at 70) if you were doing 100mph instead of 70mph, but best case scenario and you're driving the Porsche, based on the graph in the link above, and adjusting for the extra 3.5m reaction time it looks like around 30-40mph. Hitting something at that point still gives you a pretty good chance of survival in a modern car, but it's unlikely to just T-Cut out...
What speed would you be still be doing in a normal car at the ~83m point if you were doing 100mph instead of 70mph?
How much does being tired increase reaction time & stopping distance by in comparison?
Going much faster, I still find myself mentally concentrating much more - what other vehicles are doing, closing speeds, passing speeds, checking slip roads as I approach, thinking about speed cameras/vans, etc - all of that takes more mental effort as you go faster, I find.
Of course it does - you're having to increase the area you need to monitor - driving at 30mph, the stopping distance is 23m, so you only need to closely* assess hazards in that distance. At 70mph that's 96m, so you have over 4x the distance ahead which you have to watch. At 100mph, that increases to 152m, almost 7x the distance.
Its getting pretty tense in here.
Lets all play a game....
What's the fastest you have gotten to on UK motorways?
Lots of interesting points being made in here though.
In my early 20s, I managed to get my mum's 1.7 diesel Astra estate to 3 figures on the M4 at 3am once (I think it must have been down hill with a tailwind) driving to pick up my GF at the time from Stansted after her flight was cancelled. A week or so later my mum calls saying there's a letter from the police for me...
Fortunately they'd clocked me doing 53 in a temporary 40 zone, so just 3 points/£60 rather than the court & ban I was expecting!
That was enough to put me off, and since then I've stuck to the limit**
* it goes without saying that you still need to watch for things developing on the road further ahead
** other than the odd occasion when overtaking, where IMO it's safer to temporarily exceed the limit to complete the overtake quickly and minimise time spent on the wrong side of the road.