I'm 54 and use my PC for a variety of things. I have the same mind set with storage, with a wish for up to four NVMe, and the ability to run up to four Sata if required, as well as a desire to use USB 4 simply due to using external drives and absolutely hating the speeds, I want to get the Corsair EX400U USB 4 external at some point. I chose my motherboard around this. You can see the ProArt PCI lane distribution on Ronin Wilde Youtube channel, I felt it was somewhat lacking.
Still not finalized the case or GPU myself, I don't think I need a high end GPU, but at the same time feel buying anything above £500 currently is foolish as Nvidia are releasing 24gb Supers. But if I was spending with a £4k budget, wanting to game and do productivity, I would simply go all out, X3D chips are now viable since BF6 has shown it can max out the 9800X3D and as the 9950X3D is on sale, it would be pointless getting the lower model. Storage, well programs, games, general storage, movie/film/music is sort of how my mind see's things. Would prefer a 420 AIO over a 360 if there is room.
If it was going to be my last build, a 5080 Super 24gb or 5090 would be tempting if I can utilise it, though a 5070ti with 24GB also more than enough. I have a 4k 160hz monitor currently, but certainly think a 5090 would be wasted on me. A 5060ti would probably suit the majority of my games. but pointless at £400 considering the new range of Supers.
Noise is important, I like quiet, though not a fan of RGB I am tempted with the NZXT H9 RGB+ just not heard a lot of good about the fans and noise under load. But would prefer 140mm fans where possible. If I was doing productivity, editing 4k, and playing games like BF6 and wanted 4k eye candy, with £4k saved I would probably stretch to something similar to below if it was going to be my last PC and I wanted a treat. Obvioulsy substituting the GPU as required. Same with storage.
Gen 5 NVMe is about as usefull as a chocolate watch in a sauna. It can do nothing for anyone apart from a few points on a synthetic benchmark.
My basket at OcUK:
Total: £4,587.89 (includes delivery: £0.00)