Raid0 will give you a gain overall no matter what your told.
Raiding raises the seeks but as your starting of with a very low seek anyhow your better of seek wise than another other desktop HDD be it Raid or non Raid.
Most guides say 16k-32k for all round use.
4k would be great for benches but HDD would fragment frequently.
64k and upwards are starting to get into Video work although many modern Mobos set this or higher as default where as all my previous Mobos were either 16k or 32k.
You can use search and see this gets asked a lot and the same info is there as now.
Things change like XP to Vista etc, what size as most of the Windows file etc so thats how you work out whats the best Stripe for you.
No matter if you want to but 2 V-Raptors and Raid0 it will be extremely fast, lucky *******

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I also dont use Partitions, if you want to Raid0 2 HDD's and end up with 2x the Storage thats also fine I did it for Raptor X's.
Tried it before, saved me no time, 3/4 of my Games and APP's still needed reinstalled to actually run in the new Windows install, only use now if I was Beta testing which I aint since Vista and Office 11.
I will Raid 2 smaller V-Raptors if they appear, I do not need 600GB in PC at any one time, I use External for stuff moved from PC for backup.
The old story about Data loss etc, HDD's are better now than ever, obv 2 HDD's even 2x as much chance as fail, it still small and EVERYONE should have a backup be it Raid or non Raid they run.
Your PC will boot up faster, It will load some games faster (not all like old day due to way they are coded better now), it will unrar, rar up things faster.
It will just simply feel snappier.