I'll apologise also for answering here. Even though it is scientific computing, it dos'nt 100% relate to OP's question as such.
F@H is very stressfull, it will utilize 100% of your cpu, unless u tell it not to, won't go into that here. I even use it as a stress test, as iv had clocks prime stable for days, but will crash once folding.
Its stressful as you are doing mathematical calculations folding proteins, now in all honesty that goes way over my head, all i know is i run the client, it does its thing, gets sent back to Stanford, then i get more work.
So the true ins and outs of what it actually does i wouldn't be able to say, as its way above my knowledge base, the OP would probably be able to explain it better then me, by that i mean the process's of it and the coding involved.