When you say you lose your bios setting, what exactly do you mean?
Do you loose all the settings like as if the bios has done a CMOS clear. Or your settings are still shown in the bios such as XMP etc etc but when you get into windows RAM is not at XMP speeds etc.
If your bios is being reset and wiped and you have to redial all the settings then I suspect that is a motherboard hardware level issue.
however if you bios settings are still intact in bios such as XMP but when load into windows ram and CPU are not in the setting they should be at and you need to go into bios in order to activate those settings then it sounds like memory training issue or cold boot issue.
If it is cold boot issue it could also be related to PSU. Do you have another PSU to test with and how old is that 550w?
Hey brother! Basically, this problem happens every time I turn on my PC after a long period of it being turned off completely (like 12 hours of no use). When I turn it on the other day it boots normally until I get to the password screen on windows. Then, after 5 or 10 seconds it will restart itself and, fail to boot, restart itself again, gpu fans spinning 100% speed non-stop (on a normal boot they do this for 2 seconds an then stop, just AMD things) and if lt will keep like this until I turn off my PC by disconnecting the power cable from the psu. When I turn it on again it boots normally, load windows with no restart. When I check on cpuz the memory frequency is on the lowest values possible (2466mhz or something like that) and infinity fabric frequency too. When I go to the bios it starts with an message saying "yours bios settings are been reset" (this message appears in both cases, if I hit DEL and go to my bios right after the restart before loading windows or if I load windows and then restart). Everything in the bios configs are on default, including any changes I've done on it before, memory frequency, infinity fabric, everything. It shows, on the same screen that I use to load optimized defaults/save changes and exit, the 3 profiles that I made and saved with different configs, so I can assume that only the current configs on the BIOS are been reset, it's not an complete wipeout (like a CMOS reset).
My psu is an 4 year old Cougar SL 600. It's not and state-of-the-art psu, but I'm using it for all this time in my old PC (same gpu with an FX 8350 that has double tdp) and never had any problems with it. Maybe it can be something related to it being too old and not being able to handle the way my system/mobo uses the power when it's turned off for long periods of time, I don't know. It's strange, the sintoms are exactly the same as if my CMOS battery is dead, but it's not. Unfortunately I don't have another PSU to test