you can get isolator for usb https://www.amazon.co.uk/dp/B0CSYNSZ3K?th=1 almost 30quid though :S I think they were like 15 when I bought one a few years ago, it does work though.The optical out (S/PDIF) port on the motherboard (if any) will be better than usb audio, should remove buzzing from mouse pointer moving around on screen.