No. For sure not a 360 + 280. I did try a 360 + 240, but the plumbing wouldn't fit. (Maybe if i used super-thin fans?)
Maybe a 240+240 would have worked. But but that point i had given up

and i don't think 240+240 would have been enough for the components i had.
Before i moved on to what i have running now (
https://forums.overclockers.co.uk/threads/new-open-loop-build-hot-gpu-4090-fe.18974594/page-2) - photos near the bottom of Page 2
I did get the Hyte Y40 running with water. But only with a single 240x60mm thick rad. and a push-pull set of fans on it. I was hoping that would be enough, but it was nowhere near! Water was hitting 60-C
Maybe someone with more experience could make something work! Or for sure with some mods (like external rads, or maybe the rads inside, and the fans outside?) But i'm not at that level yet, and just wanted an easier case to work with for my build!
*EDIT* Yes, the side of the Y40 will support 280, but only fans (no pun intended...) A 280 rad is bigger than the space, due to the end tanks