Could this PSU handle it?

http://www.bit-tech.net/hardware/graphics/2010/07/12/nvidia-geforce-gtx-460-graphics-card-review/11

http://www.legitreviews.com/article/1373/1/

requires a 450 Watt or greater power supply with a minimum of 24 Amps on the +12 volt rail. It also requires that the power supply has two 6-pin PCI Express power connectors for proper connection. It should be noted that the NVIDIA minimum system power requirement is based on a PC configured with an Intel Core i7 3.2GHz CPU.

It should be ok, but your goin to have to use a 4pin molex to 6pin adaptor, which is not ideal.
 
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