External drive, power up 24/7 ?

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Joined
28 Sep 2004
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482
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Buckinghamshire
I'm hopefully going to be sorting out an external drive using a WD5002ABYS RE3 in an Antec MX-1 enclosure. The enclosure has an on/off switch, should this be powered up 24/7 even when my PC is off, or switch it on before powering up PC and off again after the PC has shutdown?
 
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