makes no difference, the water temp in the whole loop will equalise very quickly
shortest root = best flow = best performance
I also use 3mm thickness tube (albeit 10mm/13mm) and it is very kink resistant
90, 60 or 45 degree bends will make almost no difference either, unless you are planning on having 20 of them, if having a fitting or 2 in there helps keep the routing tidy then it's better to have it than not, having said that, looking at your routing you will have no problems getting tubing to hold those curves without kinking so you shouldn't need any bent fittings as far as I can see
will eventually (normally but) depending on volume and how cool your ambient is i run aircon in pc room so all warm airgets pumped out so my ambient doesnt vary so its always cooling if u have effecient slow water time in rad system
so basically i get a higher diferential between water and ambient all the time
i dont always beleive in shortest route is best also tbh for neatness yes but a larger volume system will be better than a small volume one, more volume = longer to ambient more heat exchange for most people.
like i said earlier it wont make much diference but some people like to have the cpu block b4 the gpu
i guess it depends on how ur pc is laid out and how u want it to look
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