Hard drive deleting files

[GJ02]

I Currently have 3 hard drives, 1 ssd as OS and small programs at the mo, 2nd is a 500gig fully bootable OS with all my files and stuff on there, what am i able to delete off the 500gig inorder to make space, im not planning on using this as a bootable drive no more.
I do have shortcuts from there to my desktop though so my program files will have to stay.
what folders can be deleted, so im still able to use my program files on the 500gig

 

[master811]

In theory you can delete any of the Windows folders (that should free up plenty of space). The other folders you will need to go through as they may or may not have data you want depending on the software you have installed.