self-publishing can be expensive and tends to have a bit of a 'couldn't get published' stigma to it (not always - there are exceptions - I think Lynne Truss of 'eats, shoots and leaves' fame started off sp'ing). Of course you have to do your own marketing too, far better if you can get deal but if not, always an option to get your work 'out there'.
As mentioned before get hold of the writers yearbook (think they now do an artist/writer split as well as the joint edition).
Find out from there which publishers are likely to be interested in the type of work you do - this also works if you have read work similar to that which you have written - if they've published work in that vein already they probably have an audience.
One thing publishers hate is people who don't follow submission rules and if you just send your stuff off willy-nilly with things on it to 'get you noticed' like ribbons, gifts, zany fonts etc, they won't even read it.
Find out who you're going to send to and what their submission requirements are. How long should your synopis be? do they want a chapter breakdown? How do they want you to format your work? Often publishers only want the first 3 chapters, single one-sided pages (for notations) with double line spacing in a 10/12 sized font. Anything else goes in the bin. Get the requirements and make sure you stick to them.
I'm sure I've got some more info around somewhere, I'll see what I can find.
Give me a shout (email in trust) if you want to ask anything else - and good luck!!)