In regards to the unmatched RAM, stick it in. If it works fine then its all good. If things start screwing up (unlikely but possible) you can almost certainly blame the RAM and just take it out again. If youre worried just do a full system backup before trying.
As far as I know changing the configuration of the RAM does not invalidate your warranty. However, I always keep my old stick just in case the computer needs to be returned to Apple (I switch out the new RAM before taking it back).