eSATA is just normal SATA but run externally so there is no difference in speed between an eSATA drive and the identical disk mounted internally so expect anything up to 85Mb/s sustained transfer (if the drive is that quick) as opposed to the 20Mb/s or so that USB2 will give you.
The connector is slightly different to stop it falling out so standard SATA cables are no use but any eSATA device will come with a cable.
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