Your build is very similar to mine.
I have the same 50" TV and the same HTPC case

I'm however using an
E2140 which i have overclocked to 2.6Ghz which is being cooled by a
Scythe Mini Ninja running at 800rpm (silent!). I'm also using a single
Noctua case fan which is running at 1000rpm. The motherboard is a
Abit Fatality F-190HD (sadly discontinued) which has X1250 on-board 1080p graphics.
Its virtually silent and even with the fans running at lowest settings the temps idle at 40*C and under load reach no more than 55*C.
I've also got a harmony remote to control the HTPC.
Your speakers are a little low placed. Have you considered gettings some stands?
I would move the centre speaker to the shelf above.