I run a 2.1 setup in my home office. Basically I run an Edifier S530, however I have changed the speakers to larger Edifier speakers.
So it's this system below.
https://www.edifier.com/my/en/speakers/s530d-2.1-subwoofer
The problem with the stock S530 satalite speakers is as mentioned in previous post, the mid range unit is to small and vocals are not correct with a gap in frequency. The S530 gets really good reviews but to me it's just more evidence of people not knowing what they are listening to, probably the same group of people who say motherboard audio is as good as sound cards, before taking any advice on the internet always consider the person giving you that advice first.
Anyhow to solve the mid-range issue the standard satellite speakers have been changed to the following.
It's then setup so the base unit is only providing gentle support for the satellites, when I hear music I can't detect a bass unit is in place, however I notice a reduction in sound quality if the bass unit is disabled. So the bass unit is invisible if that makes any sense, as the overall sound just appears to my ears to be coming from the left and right satellites.
This source for all above is a Asus Essence ST, I replaced the speaker cable with thicker cable, added foam installation and stands, and use a main conditioner. The speakers are rotated but I tried them at all angles and that is what sounded best to me.
And as for sound quality it's honestly pretty good, downstairs I have proper Pioneer separates and Yamaha floorstanding speakers, and i'm not unhappy by the quality of this hybrid 2.1 system I have created.
Also if anyone is interested settings on the Edifier S530 go from -6 to +6 for bass, treble and bass, however everything is run at 0 so everything is totally neural. A general rule of thumb for any hifi/music is if you can have the settings or graphics equalizer at neutral and it sounds good, then the actual equipment is pretty balanced at a hardware level. If you ever have a setup and your making large changes, including changes in any software EQ it's an indication something is wrong.
And a quick note on the stands and foam installation. These are vital to improve sound, speakers should be at ear level and positioned correct. The foam stops vibration into the desk and helps isolate the sound. I see plenty of people with expensive speakers and placing them directly on the desk. Well here is a question, would you fit expensive coil-overs to your car, then drive with worn out suspension bushes and the geometry wrong? Of course not as the car would be crashy and not handle correct. When you put speakers directly on a desk no mater how much they cost this is what your doing with the sound if the speakers are not isolated and positioned correctly.