M.2 Drive in MB

[ZX-10R]

I've been out of PC Building a while.

I see that Most MB have a M.2 PCI.4 slot and two others that have PCI.3 slots
if I was populating all 3 with a gen 4 and 2x gen 3.
where would it be best to install OS, games. Programs & data?
I may be getting it all wrong so Looking for advice.

 

[ZX-10R]

something along these Lines the 4t Drive is so back up, I'd be using My Current 1000W PSU


My basket at OcUK:

• 1 x Intel Core i7-11700K 3.6GHz (Rocket Lake) Socket LGA1200 Processor - OEM (SKU: CP-691-IN) = £344.99
• 3 x Crucial P5P 1TB M.2 2280 PCI-e 4.0 x4 3D NAND NVMe Solid State Drive (SKU: HD-074-CR) = £112.99
• 1 x Lian Li O11D EVO Mid-Tower Case - White (SKU: CA-7A5-LL) = £159.95
• 2 x Team Group Night Hawk RGB 16GB (2x8GB) DDR4 PC4-25600C16 3200MHz Dual Channel Kit - RGB White (TF2D4 (SKU: MY-08N-TG) = £89.99
• 2 x Lian-Li UNI AL120 Addressable RGB White 120mm Fan Triple Pack with Controller (SKU: FG-00V-LL) = £82.99
• 1 x Asus ROG Strix Z590-A Gaming WIFI (Socket LGA 1200) DDR4 ATX Motherboard (SKU: MB-6FZ-AS) = £289.99
• 1 x Asus & Gamesplanet - Game Promo (SKU: XX-03R-AS) = £0.00
• 1 x Asus GeForce RTX 3080 ROG Strix WHITE OC V2 LHR 10GB GDDR6X PCI-Express Graphics Card (SKU: GX-46W-AS) = £929.99
• 1 x Lian Li O11D EVO Vertical GPU Kit – White (SKU: CA-7A8-LL) = £59.99
• 1 x WD 4TB Blue HDD 5400rpm 256MB Cache Internal Hard Drive (WD40EZAZ) (SKU: HD-57S-WD) = £77.98

Total: £2,562.53 (includes delivery: £14.70)​

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