Haven't played Skyrim but I would imagine it makes a good starting point, personally when attempting a new genre for the first time I would always recommend modern games (providing they are highly rated of course) as they tend to be more streamlined and easier to get in to. Then once that's out of the way you can explore back-catalogues from Bethesda, Bioware etc.
You mean Bioware, Black Isle Studios, Interplay and Troika?
