Is your 780ti overclocked? If so I have a suggestion. I had something similar to what you are seeing with my dual 780's in SLI. When I first installed them I overclocked them, ran them through unigine multiple times and no issues. I gamed for quite some time with zero problems but mostly just the same two games, then one day I decided to try a new game which was Paladins. When playing that, my game just kept freezing randomly, like the screen would totally freeze even though everyone else in the match would play as normal so I would get killed just standing there. As well as the freezes It would occasionally crash. I can't remember if I tried a different game as it was a long time ago now but long story short i literally checked everything I could think of, tested the RAM, monitored all temps, installed the game on two different HDDs, reinstalled drivers, downgraded from Win 10 back to Win 8.1...did a fresh Windows install, literally nothing worked. Just as I was going to give up I found some obscure post through google where someone was having similar issues and it turned out his overclock wasn't as stable as he thought, it seemed fine 99% of the time but for whatever reason in certain games he would get crashes. So as a last ditch effort I removed my overclock, reset it back to factory settings and boom. Never had a single issue ever since, I played Paladins for weeks without a single freeze or crash (until i eventually got bored of that game). Give it a try if it is applicable for you.