I think pill cartons have AI built in to send the instruction leaflet to whichever end it detects you opening. I would say my leaflet hit rate is about 75%, and if I do get the leaflet end I will rip the box open like a lion feasting on a still live warthog in the Serengeti. Guess what Youbube Recommendations thought I ought to be watching in the last few days. Not just lions, Wild Dogs as well, but mainly warthogs. Lions never have to bother which end to open up first though, its always the arse end.