Looking at the original post OP had done a clean install of Windows drivers should have been fineOne thing that I discovered, moving from the 30 series to the 40 series, was, did you use DDU and then reinstall the drivers?
I was getting problems until someone suggested doing that, and it worked.
DDU makes sure that the old driver is fully removed before you install new. It solves many issues!
Unless you use the speakers in the monitors, I would remove the NVIDIA audio driver. Again, I had to do that with my monitors.
I see your using multiple monitors, have you tried with just 1 monitor connected?
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