Cisco Call Manager Express can do Video Conferencing using Cisco VT Advantage. Depends on how rugged you want the solution to be, is this for home use or business?
Also how many attendants would you want in a single conference?
X-Lite from Counterpath, http://www.counterpath.com
It's free but you'll need to rely on your VPN for security. If you want encryption between the end points then you'll need the registered version, eyeBeam. Both products support multi-party conferencing.
Polycom PVX, http://www.polycom.co.uk
Has lots of features - shared desktop, able to send media content to remote end like presentations and videos. Will support point to point but multi-party setup will require additional hardware/software. It's a registered product but you can download it for a 30 day trial.
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