The answers are in the thread if you read it!
If you want to use something like E85 you need to get the car remapped, and may need larger injectors since they will be flowing quite a bit more fuel. To take advantage of the higher octane the compression ratio needs to be raised, obviously this means you can no longer safely run on standard unleaded. You will also need to check that all parts of the fuel system are compatible with ethanol based fuels.
(my emphasis): no, you just need to advance the ignition. If my car was remapped for E85 I'd get about another 30-40 bhp (call it 8-10%) almost entirely from the ignition - I believe another 3-5 degrees is possible. On an auto-adjusting ECU you can go back to odinary unleaded and the ECU will just retard the ignition again as soon as it detects the inevitable det. But you will probably struggle to advance the ignition very far just by running E85 without the map.
M