As long as you remain within the bandwidth limits, you shouldn't see any effect, adverse or otherwise, between having your drives on the same channel or on separate channels. SCSI will cope fine having 15 drives on a single channel, but it won't be optimal.
You should try not to put more drives on a single channel that there is available bandwidth on that channel, eg:
1x 15k drive ~= 100MB/s on a u160 channel = fine, 60MB/s bandwidth left
2x 15k drive ~= 200MB/s on a u160 channel = not optimal
For best performance :
1x 15k on each u160 channel
2x 10k on each u160 channel
2x 15k on each u320 channel
4x 10k on each u320 channel
Having said that, you _may_ find better performance spreading your drives out equally over the channels you have, then transfers to/from the drive cache will be faster.