Yes, several S478 boards supported DDR2, but you'd most likely only get a really good one second hand now. If you've not already done so, get onto Member's Market wanted pages and ask for offers.
If you just want a board then typing "S478 motherboard DDR2" into froogle.co.uk will chuck up a couple of perfectly respectable boards. The Intel 945 chipset was about the best that S478 ever got to.
I think there are actually only 2 boards - the ASRock and the Biostar, and of the two I'd buy the ASRock as it has an Intel 945 chipset whereas the other has a VIA chipset which isn't as fast or as feature rich.
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