There are a few big differences:
- CPU cooler clearance is limited to 72mm.
- GPU clearances, while adequate, are comparatively tight.
- Flow-through GPU coolers (i.e. Nvidia 3000-Series FE cards) are likely to be problematic.
- Drive support isn't as good, unless you use a really short GPU.
- For W/C you're limited to one 280mm rad (albeit you can likely squeeze a 45mm thick one in there).
Also, testing is more of a mixed bag when you take a closer look. The Meshlicious is
very good. But that headline grabbing 7° lower CPU temp came at a cost; GPU thermals were 8° higher. Flip the airflow and CPU temps are about the same (but at a lower noise level), while GPU temps are still 6° higher. With NR200 supporting larger GPU coolers, there's potential for this difference to be even bigger.
Also, I wouldn't bank on availability. Ali is wrong about where the case comes from. It isn't a Lian Li sub-brand, or a partnership between Ncase and Lian Li. It's a project by Wahaha360 (one of the creators of Ncase). For production, he buys up spare machine time at Lian Li's factories. Every other case produced using this method (e.g. Ncase, FormD T1, Dancase A4) has spotty availability.