Hey Panos, I'm using 2 watercooled Sapphire Nanos and tried to confirm this for you. Only thing is, it doesn't look like I can input the same settings as you in Trixx.
My default Trixx settings are:
GPU clock: 1000MHz
GPU voltage: +0mV
Power Limit: 0%
Memory Clock: 500MHz
Fan Control: Automatic
I can't however set the memory clock to 1100 MHz like you, the max that Trixx allows me to go to is 750MHz.
The Max GPU clock that trixx allows me to go to is 1700MHz, but I haven't set it that far and in fact I haven't yet found the stable overclock settings for these cards.
In fan control alternating between the fixed and default (I assume you mean automatic) options doesn't change anything as far as I can tell.
I'm using Trixx version 5.2.1. Should I be able to input the same settings as you? If I could get some clarification with what's going on on my end I might be able to replicate this peculiarity.